Headspace gas chromatography

SDFCL’s - Gas Chromatography-Headspace (GC-HS) Analysis: High-Purity Solvents for Residual Solvent Detection

February 7, 2025

Introduction

Gas Chromatography-Headspace (GC-HS) analysis is a specialized technique used for detecting and quantifying residual solvents and volatile organic compounds (VOCs) in pharmaceuticals, food products, and industrial samples. This technique is particularly valuable in compliance with ICH Q3C guidelines, ensuring that solvent impurities are within permissible limits.

The success of GC-HS analysis heavily depends on the use of high-purity solvents, which provide batch-to-batch consistency, low residue, and minimal evaporation loss. SDFCL's GC-HS grade solvents are specifically designed for ultra-trace analysis, ensuring maximum sensitivity and accuracy in analytical testing.