Acetonitrile for ULC-MS : A High-Purity Solvent for Advanced Analytical Applications

In the world of analytical chemistry, precision and accuracy are critical for research,
pharmaceuticals, environmental analysis, and more. One powerful technique that has
revolutionized chemical analysis is ULC-MS, short for Ultra Liquid Chromatography-Mass
Spectrometery. At SD Fine-Chem Limited, a trusted name in the chemical manufacturing
industry, ULC-MS plays a vital role in ensuring the purity, quality, and performance of
products globally .

ULC is an advanced form of liquid chromatography with higher resolution, faster analysis
times, and improved sensitivity compared to conventional HPLC as well as Mass Spectrometery is a powerful tool for detecting and identifying compounds based on their mass-to-charge ratio (m/z).

Key Characteristics of ULC-MS Grade Acetonitrile
● High Transmittance – Ensures accurate and reliable detection of analytes.
● Stable Flat Baseline with Minimal Drift – Provides precise and reproducible results.
● Pre-Filtered with 0.2 µm Filter – Reduces particulate contamination and enhances
performance.
● Packed with Inert Teflon Plug – Maintains solvent integrity by preventing contamination
under a nitrogen blanket.
● Extremely Low UV Absorbance – Ensures optimal optical clarity for UV detection.
● Very Low Non-Volatile Residue – Prevents interference in sensitive mass spectrometry
analysis.

Range of ULC-MS Grade Products
S D Fine-Chem Limited offers a comprehensive selection of high-purity solvents, including:
● Acetonitrile for ULC-MS
● Acetonitrile with 0.1% (v/v) Formic Acid for LC-MS
● Acetonitrile with 0.1% (v/v) Trifluoroacetic Acid for LC-MS
● Methanol for LC-MS
● Triethylamine for ULC-MS
● Acetic Acid for ULC-MS
● Ammonium Acetate for ULC-MS
● THF : Tetra Hydro Furan for ULC-MS
● IPA : Iso Propyl Alcohol for ULC-MS

These solvents are available in various pack sizes of 1.0 L, 2.5 L, and 4.0 L, ensuring
flexibility for different laboratory requirements.

Why Choose SD Fine-Chem Limited for ULC-MS Acetonitrile?
● Competitive Quality and Pricing – Equivalent to international brands at a cost-effective
price.
● Minimal Gradient Drift – Enhances sensitivity for detecting lower concentrations of
impurities.
● Strict Quality Control – Rigorous testing and inspection ensure consistency and
reliability.
● High-Quality Packaging – Imported bottles with an inert Teflon plug extend shelf life
and maintain solvent stability.
● Ready Stock Availability – Ensures quick delivery for laboratory and industrial needs.

Analytical Performance
Acetonitrile for ULC-MS undergoes strict testing, including gradient elution tests and 3D
chromatographic analysis (190-400 nm by PDAD with Water ULC-MS) . This ensures superior
performance, reproducibility in high-precision analytical workflows.

Conclusion
For laboratories and industries requiring ultra-high purity solvents, SD Fine-Chem Limited’s
ULC-MS Grade Acetonitrile offers an excellent combination of performance, reliability, and
cost-effectiveness. With rigorous quality control and innovative packaging, our acetonitrile
ensures optimal results in mass spectrometry and chromatography applications